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Abstract
The main principle of the automated blood analyzers is to get the quantity (count) of different blood components (parameters) in the peripheral blood samples. Additionally, in case of Sysmex KX-21 blood analyzer, the work performance includes also 3-part differential white blood cells (WBC) count represents eight parameters of the complete blood count (CBC). Extremely important to mention here
that many of the analyzed information about the main blood corpuscular are provided in graphical forms called histograms. Remarkably, any abnormal results in the investigated blood parameters due to multi different factors such as red blood cell fragments, platelets clumps, cold agglutinins, giant platelets and many other factors will appear in an abnormal histograms and flags. These abnormalities in values and histograms or flags appeared are due to be interpreted and adjusted depending on extensive knowledge of the analytic performance of the analyser and the clinical
significance of the results they provide. As the KX-21 is a fully automated haematology analyser, easily fitting into a lot of medical laboratories in our country and ideal as a backup analyser to the Sysmex full differential analyser system, we tried to create a scientific method (it can be in a hard or soft copy) to avoid automating bad work processes. This is carried out in order to get accurate results, to interpret different histograms in a good way and to discover the reasons lead to appearance of the flags during analysing.